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Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/22/2023 1:22:01 PM
Research Description
Biochemistry of DNA replication and repair; dynamic protein DNA interactions and enzyme mechanisms required for these processes.
Department:
Oral Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
7/13/2023 11:38:20 AM
Research Description
Streptococcal protein translocation; stress responses; membrane biogenesis; biofilm formation; bacterial adhesion; functional amyloid formation; host/pathogen interactions; immunomodulation by monoclonal antibodies; structure/function of streptococcal sur
Department:
Medicine
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
No
Last Updated
6/22/2023 1:22:52 PM
Research Description
The goal of our work is to understand how misfolded alpha-1-antitrypsin causes cellular injury in liver and innate immune cells and to develop rational therapies to modulate this injury. To accomplish this goal we use cellular and animal models and transl
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/22/2023 1:10:48 PM
Research Description
Cell biology and biochemistry of actin-binding proteins involved in apoptosis, angiogenesis, neural plasticity and cancer biology.
Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/22/2023 1:22:29 PM
Research Description
Analysis of long distance gene regulation by enhancers and locus control region. Genomic and proteomic analysis of erythroid transcription factors. Modulation of gene expression using synthetic zinc finger proteins.
Department:
Oral Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/13/2023 2:30:51 PM
Research Description
Environmental regulation of bacterial gene expression and virulence.
Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/14/2023 2:33:22 PM
Research Description
The lab study DNA repair to understand how the repair proteins coordinate to deal with DNA damage. We use biochemistry and enzyme kinetics in combination with X-ray crystallography and Cryo-EM to uncover the structures of repair proteins engaging with damaged DNA at atomic resolution.
Department:
Pathology, Immunology & Laboratory Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
7/13/2023 11:37:07 AM
Research Description
kidney development, regenerative biology and disease
Department:
Food Science & Human Nutrition
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/16/2023 2:15:25 PM
Research Description
Molecular and cell biology of zinc metabolism and function.
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/16/2023 1:52:50 PM
Research Description
Metabolism-Diabetes (T2DM); Obesity; Fatty Liver Disease (NAFDL). The main goals of our lab are to understand the metabolic and molecular pathways of T2DM, obesity and NAFLD.
Department:
Physiological Sciences
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/15/2023 12:49:45 PM
Research Description
Her research involves developing and using molecular biomarkers to evaluate changes in gene expression depending on stress or exposure to contaminants.
Department:
Molecular Genetics & Microbiology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/16/2023 1:50:41 PM
Research Description
O) Research Interest: Gene expression must be accurate in theory, however mRNA translation is surprisingly error-prone with 10% of nascent proteins having at least one error. These error products could stimulate protein aggregation with a progressive deterioration of protein homeostasis across aging. We approach disruptions in protein homeostasis from a protein production standpoint to understand how error products contribute to protein aggregation and the late onset of age-related neurodegenerative diseases. Our lab’s study of molecular mechanisms of translation error using cutting-edge biochemistry, molecular biology, and state-of-the-art genomics in yeast, mouse embryonic stem cell culture, and in vivo mouse models. We will provide crucial insight for the development of therapies for neurodegenerative disease.
Department:
Pathology, Immunology & Laboratory Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
7/8/2022 1:20:38 PM
Research Description
His main research interests are the development of novel mass spectrometry technologies for clinical research such as metabolomics, lipidomics, and direct analysis mass spectrometry applied to biomedical applications. His lab also works on bioinformatics to help identify novel metabolites and develop software to improve data analysis.

Matthew S. Gentry, Ph.D.

Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/14/2023 3:10:47 PM
Research Description
The Gentry laboratory defines disease mechanisms and develops disease-modifying therapies for diseases including Alzheimer’s disease, Lafora disease, lung adenocarcinoma, Ewing sarcoma, Glycogen Storage Diseases, and others. The laboratory utilizes structure/function techniques, biochemical assays, cell biology, genetically modified mouse models, human samples, and cutting-edge metabolomics techniques.
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
7/13/2023 12:02:47 PM
Research Description
The Gumz laboratory is investigating the role of the circadian clock in the kidney and cardiovascular system. We use transgenic rodent models to determine the role of the molecular clock in the regulation of fluid and electrolyte balance, which is critical to the control of blood pressure as well as to overall cardiovascular health.
Department:
Medicine
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/15/2023 2:46:26 PM
Research Description
Development of anti-infective countermeasures for bacterial infections of bio-warfare or bio-terrorism potential. Development of aerosol infection models.
Department:
Orthodontics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
7/8/2022
Research Description
Regulation of bone remodeling and the generation of new tools for the treatment of bone disease. Recent studies are focused on extracellular vesicles (exosomes) involved in regulating bone remodeling and on the generation of bone biomimetics.
Department:
Anatomy & Cell Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/22/2023 12:58:27 PM
Research Description
Chemoresistance in breast and prostate cancer, Nuclear Structure and Function, Epigenetic Regulation of Gene Expression. tumor Suppression
Department:
Pathology, Immunology & Laboratory Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
7/24/2017
Research Description
Microbial pathogenesis, antibiotic resistance, microbial genetics, molecular epidemiology, microbial ecology.
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/22/2023 1:02:17 PM
Research Description
Dr. Kaye has a longstanding research interest in cancer genetics and translational clinical research. His lab studies the functional properties of a cAMP/CREB/CRTC pathway that is activated in cancer by loss of LKB1/AMPK signals in lung cancer. He also studies oncolytic virotherapy for small cell lung cancer with plans for a phase 1 clinical trial.
Department:
Pharmacodynamics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
7/13/2023 11:49:40 AM
Research Description
My research interests are the adaptations in endocrine and cardiovascular systems in pregnancy and at birth. The current focus of my research is fetal and neonatal metabolism, including 1)the effect of glucocorticoids on fetal cardiac metabolism and function, and the transition at birth, 2) effects of exposure to Triclosan (an antibacterial in many soaps), and 3) alterations in the maternal microbiome. The laboratory uses a combination of in vivo techniques, including use of telemetry to measure fetal cardiovascular function in utero, biochemical techniques, and systems biology methods- both transcriptomics and metabolomics.
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/28/2023 3:21:09 PM
Research Description
The research in Dr. Khemtong’s group is focused on understanding intermediary metabolism using stable isotope tracers, primarily carbon-13, combined with magnetic resonance and mass spectrometry techniques. His group is also working on real-time imaging of metabolic processes using hyperpolarized carbon-13 MRI.
Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
7/13/2023 10:58:59 AM
Research Description
Mammalian cell culture systems. Epigenetic regulation of transcription; chromatin structure and function; epigenetic silencing of tumor suppressor genes in cancer; single-molecule analysis of chromatin structure
Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/15/2023 8:12:57 AM
Research Description
Development, Implementation and Evaluation of a variety of research-aligned programs linking UF research faculty and graduate students with precollege science teachers, talented high school students, and underserved schools and communities across Florida
Department:
Periodontology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/20/2022
Research Description
Role of dominant microRNAs in periodontal disease (Current new Funded study). Major interests are to examine the role of major periodontal pathogens causal association with systemic diseases including Alzheimer’s disease, atherosclerosis, and rheumatoid arthritis.
Department:
Physiology & Functional Genomics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
7/13/2023 11:35:07 AM
Research Description
Physiology, biology & biochemistry of aging, with focus on mitochondrial biology, autophagy, apoptosis, oxidative stress, anti-aging interventions and translation to clinical trials based on findings from pre-clinical models.
Department:
Medicinal Chemistry
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
7/13/2023 12:09:33 PM
Research Description
Li’s scholarly interests range from organic chemistry, biochemistry, medicinal chemistry to physical chemistry, computational chemistry, molecular biophysics and pharmacology. His research focuses on molecular recognition, with a strong application to structure-based drug dresign, especially for anti-cancer and neurodegenerative diseases.
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/14/2023 2:28:08 PM
Research Description
Jonathan D. Licht, MD, is the Director of the University of Florida Health Cancer Center, Dr. Licht's laboratory studies aberrant epigenetics and gene regulation as a cause of hematological and other malignancies
Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
7/6/2022 4:49:08 PM
Research Description
Protein structural biology; protein regulation of biofilm formation; Interaction of proteins and membanes in regulating cell membrane biophysics and pulmonary surfactant; nuclear magnetic resonance (NMR)
Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/22/2023 1:07:00 PM
Research Description
Epigenetic and metabolic regulation of tumor progression and therapeutic resistance.
Department:
Neuroscience
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
7/8/2022
Research Description
Application of gene transfer to study animal models of neurodegenerative disorders including Parkinson's disease, Huntington's disease, brain tumors, and ischemia.
Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/22/2023 12:35:41 PM
Research Description
The study of central nervous system structure and function with magnetic resonance. In particular, mapping of brain structural connectivity using diffusion-weighted magnetic resonance imaging methods, functional connectivity with functional magnetic resonance imaging and function with magnetic resonance spectroscopy.
Department:
Environmental Health
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/13/2023 1:33:47 PM
Research Description
Pathogenic mechanisms of Shigella and Chlamydia
Department:
Molecular Genetics & Microbiology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
7/8/2022
Research Description
Focused on the use of statistical theory to elucidate the relationship between genotype and phenotype. Currently interested in integration of omic data.
Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
7/13/2023 11:31:18 AM
Research Description
Multidisciplinary approaches: including molecular biology, biophysical techniques, structural biology (cryo-EM and crystallography), and kinetics are used to study biological molecules (viruses and proteins)
Department:
Infectious Diseases and Immunology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/23/2022
Research Description
Host and viral protein interactions relevant to therapeutic and vaccine development, Retrovirus vector for gene transfer based on foamy virus.
Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
7/10/2023 2:30:09 PM
Research Description
The Merritt lab is dedicated to understanding intermediary metabolism through the process of measuring metabolic flux quantitatively in living systems, including cell culture, perfused organs, and in whole animal models.
Department:
Anatomy & Cell Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/22/2023 12:47:11 PM
Research Description
Development of novel therapy for colorectal and breast cancers.
Department:
Restorative Dental Sciences
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/17/2022
Research Description
My main research projects focus on investigating the relationship between oral alkali production from arginine and dental caries experience in children and adults.
Department:
Neuroscience
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/17/2022
Research Description
Our research focuses on understanding the underlying molecular mechanisms controlling gene expression in the inflammatory response and in the etiology of Type 1 Diabetes.
Department:
Pathology, Immunology & Laboratory Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
7/13/2023 11:11:14 AM
Research Description
Immune recognition, structural biology and drug discovery; cancer research; immunological regulation by T cells; structural interactions defined by X-ray crystallography and functional studies; drugs to prevent and treat COVID-19 .
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
7/8/2022 3:11:41 PM
Research Description
The long-term goal of my research is to understand the mechanisms that underlie the development of blood cancers with a focus on studying the genetic pathways that control the proliferation, survival and self-renewal of normal or leukemic hematopoietic stem cells. The current main research focuses: 1. Molecular regulation of normal hematopoietic stem cell (HSC) and its leukemic transformation 2. The role of the Wnt/beta-catenin signaling in the development and maintenance of myeloid neoplasms 3. Transcriptional, epigenetic and epitranscriptomic regulation of normal hematopoiesis and leukemogenesis 4. Development of targeted therapies for myeloid malignant diseases
Department:
Pathology, Immunology & Laboratory Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/20/2022 2:03:34 PM
Research Description
Molecular evolution of viruses, with special emphasis on HIV/SIV and SARS-CoV-2. Development and application of new bioinformatics and phylogenetic analysis tools to investigate the molecular epidemiology of microbial pathogens, with emphasis on RNA-virus
Department:
Whitney Laboratories
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/14/2021 3:39:49 PM
Research Description
Research focus:the cellular and molecular mechanisms of development and regeneration in annelids and other closely related marine animals. Interests: patterning of embryonic stem cells, neurogenesis, regenerative biology and patterning of the germline.
Department:
Physiology & Functional Genomics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/22/2023 1:20:33 PM
Research Description
Molecular and cellular mechanisms underlying sex difference in hearing, cochlear aging, and hearing loss using genetic mouse models.
Department:
Pediatrics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
7/12/2023 12:57:29 PM
Research Description
For more than four decades, Dr. Srivastava’s research has been focused on the basic molecular biology of a non-pathogenic adeno-associated virus (AAV), and the development of the next generation of recombinant AAV vectors. The current emphasis is on gene therapy/genome editing of human blood diseases.

Ramon C. Sun, Ph.D.

Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
No
Last Updated
11/28/2022
Research Description
Dr. Sun is a leading expert in spatial metabolomics, and his lab focuses on understanding the molecular events connecting complex carbohydrates to cellular metabolism, signaling and physiology, with a strong emphasis on disease etiology of neurological disorders.
Department:
Oral Biology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
7/13/2023 11:58:20 AM
Research Description
We study the molecular and cellular mechanisms of lifelong herpesvirus infections, focusing on the cancer-causing DNA virus called KSHV. We use KSHV mutants, proteomics, RNA and recombinant DNA technologies to identify and investigate the viral and host factors that are crucial in the regulation of KSHV infection.

Craig W. Vander Kooi, Ph.D.

Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/22/2023 12:57:32 PM
Research Description
Dr. Vander Kooi is a recognized expert in using the tools of structural biology to define fundamental biology and translate these insights into biomedically and translationally relevant applications.
Department:
Molecular Genetics & Microbiology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/15/2023 12:23:01 PM
Research Description
Mutation and analysis of human disease susceptibility genes, and tumor genetics.
Department:
Physiology & Functional Genomics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/22/2023 12:45:21 PM
Research Description
Measurement of skeletal and cardiac muscle physiology, function, and metabolism using innovative NMR and MRI based techniques. Studies the effect of gene transfer/pharmacological correction from the basic cell level to humans with muscular dystrophies.
Department:
Molecular Genetics & Microbiology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/16/2021
Research Description
We study microsatellite repeat expansion diseases, including myotonic dystrophy. We use molecular, cellular, computational, and animal-based approaches to understand basic mechanisms that cause symptoms in this and related multi-systemic diseases, as well as identify treatments that will help patients. We also study RNA localization at a basic level, to understand why and how RNA molecules move to different places in the cell. We seek to combine high-throughput genomics approaches with single molecule imaging approaches to characterize and understand this new frontier in biology.
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/10/2021 8:44:59 AM
Research Description
Aldosterone action & hyperaldosteronism, renal endothelin action, hypertension, ion transporting ATPases; K+ channels; signal transduction.
Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/22/2023 12:44:33 PM
Research Description
The Xie Lab’s research interest is to decipher molecular mechanisms that modulate RNAs essential for gene expression in metazoans and associated Herpesviruses. Our current focus is on microRNAs, small non-coding RNA molecules that control the function of other genes. In the near future, we will integrate approaches from biochemistry, cell biology, virology and bioinformatics to study viral and cellular non-canonical microRNA biogenesis pathways, which surprisingly incorporate several fundamental cellular machineries involved in processing other classes of RNAs. Our efforts will provide a better basis for developing novel therapeutics that alter microRNA levels to combat a variety of diseases, including Herpesvirus-induced malignancies and other cancers.
Department:
Surgery
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
7/13/2023 11:30:26 AM
Research Description
1. Optimization of multi-component complex systems 2. Drug resistance mechanisms in liver cancer 3. Immune metabolism in organ injury and transplantation 4. Mechanisms and health disparities in fatty liver disease
Department:
Pediatrics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
7/13/2023 12:21:46 PM
Research Description
Gene Therapy, AAV vector design, AAV vector production, Directed Evolution, Machine Learning.

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