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Department:
Oral Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/10/2021 3:08:32 PM
Research Description
My research area is to elucidate the regulatory pathways of oral bacteria, with particular focus on biofilm formation and stress tolerance that can modulate the virulence of oral bacteria and enhance the pathogenic potential of oral biofilms. Stemming from the original AtlA work, another major research area is to investigate the molecular basis for regulation of autolysis of S. mutans by gene products that have major effects on traits related to virulence. This research focuses on the characterization of a pair of dicistronic operons, lrg and cid-like, that significantly affected autolysis and biofilm formation by S. mutans.
Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/15/2021 12:55:54 PM
Research Description
Biochemistry of DNA replication and repair; dynamic protein DNA interactions and enzyme mechanisms required for these processes.
Department:
Oral Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/10/2021 11:11:38 AM
Research Description
Streptococcal protein translocation; stress responses; membrane biogenesis; biofilm formation; bacterial adhesion; functional amyloid formation; host/pathogen interactions; immunomodulation by monoclonal antibodies; structure/function of streptococcal sur
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
7/8/2019
Research Description
The goal of our work is to understand how misfolded alpha-1-antitrypsin causes cellular injury in liver and innate immune cells and to develop rational therapies to modulate this injury. To accomplish this goal we use cellular and animal models and transl
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/12/2017 9:11:54 AM
Research Description
Cell biology and biochemistry of actin-binding proteins involved in apoptosis, angiogenesis, neural plasticity and cancer biology.
Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/10/2021 1:34:32 PM
Research Description
Analysis of long distance gene regulation by enhancers and locus control region. Genomic and proteomic analysis of erythroid transcription factors. Modulation of gene expression using synthetic zinc finger proteins.
Department:
Oral Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/9/2021 2:30:51 PM
Research Description
Environmental regulation of bacterial gene expression and virulence.
Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/14/2021
Research Description
Functional, cellular and structural characterization of base excision DNA repair proteins to understand the molecular mechanism of oxidative DNA damage processing using multifaceted approach including DNA repair assays in vitro, biophysical protein-protein and protein-DNA interaction measurements in real time, X-ray crystallography/Cryo-EM studies, cell viability analyses in vivo
Department:
Pathology, Immunology & Laboratory Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/10/2021 12:12:32 PM
Research Description
kidney development, regenerative biology and disease
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/23/2020
Research Description
Mycobacterium tuberculosis, the causative agent of tuberculosis. Investigate how these bacteria survive and grow within human cells to cause TB. We are using this knowledge to develop a safe, effective vaccine to protect people against infection. We are expanding our research focus to include development of a vaccine to protect against infection by non-tuberculous mycobacteria (NTMs), especially M. abscessus and M. avium.
Department:
Physiology & Functional Genomics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
7/5/2019
Research Description
Investigation of renal, cardiovascular, placental and endometrial function in normal and pathological pregnancies
Department:
Food Science & Human Nutrition
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/14/2021 4:54:54 PM
Research Description
Molecular and cell biology of zinc metabolism and function.
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/10/2021 1:11:23 PM
Research Description
Metabolism-Diabetes (T2DM); Obesity; Fatty Liver Disease (NAFDL). The main goals of our lab are to understand the metabolic and molecular pathways of T2DM, obesity and NAFLD.
Department:
Physiological Sciences
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/15/2020
Research Description
Environmental reproductive toxicology in wildlife.
Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/9/2021 3:23:37 PM
Research Description
Molecular biology and genetics of RNA virus replication. Development of noninfectious VLP vaccines for poliovirus and other picornaviruses.
Department:
Molecular Genetics & Microbiology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/10/2021 2:01:40 PM
Research Description
Dr. Fujii's research is centered on understanding of the gene regulation, focusing on the step of mRNA translation. His research program will unravel new layers of spatiotemporal specificity and fidelity of protein synthesis, to further understand the impact of translational regulation in normal and disease conditions.
Department:
Pathology, Immunology & Laboratory Medicine
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/10/2021 1:20:38 PM
Research Description
His main research interests are the development of novel mass spectrometry technologies for clinical research such as metabolomics, lipidomics, and imaging mass spectrometry applied to biomedical applications. His lab also works on bioinformatics methods to better understand the complexity of data generated.
Department:
Medicine
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/10/2021 8:49:01 AM
Research Description
The Gumz laboratory is investigating the role of the circadian clock in the kidney. The focus is on the regulation of renal sodium and potassium handling, which is critical to the control of blood pressure as well as to overall cardiovascular health.
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/10/2021 4:57:16 PM
Research Description
Development of anti-infective countermeasures for bacterial infections of bio-warfare or bio-terrorism potential. Development of aerosol infection models.
Department:
Orthodontics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/30/2020
Research Description
Regulation of bone remodeling and the generation of new tools for the treatment of bone disease. Recent studies are focused on extracellular vesicles (exosomes) involved in regulating bone remodeling and on the generation of bone biomimetics.
Department:
Anatomy & Cell Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/15/2021 1:03:15 PM
Research Description
Chemoresistance in breast and prostate cancer, Nuclear Structure and Function, Epigenetic Regulation of Gene Expression. tumor Suppression
Department:
Pathology, Immunology & Laboratory Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
7/24/2017
Research Description
Microbial pathogenesis, antibiotic resistance, microbial genetics, molecular epidemiology, microbial ecology.
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/30/2020
Research Description
Dr. Kaye has a longstanding research interest in cancer genetics and translational clinical research. His lab studies the functional properties of a cAMP/CREB/CRTC pathway that is activated in cancer by loss of LKB1/AMPK signals in lung cancer. He also studies oncolytic virotherapy for small cell lung cancer with plans for a phase 1 clinical trial.
Department:
Pharmacodynamics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/10/2021 4:07:43 PM
Research Description
My research interests are the adaptations in endocrine and cardiovascular systems in pregnancy and at birth. The current focus of my research is fetal and neonatal metabolism, including 1)the effect of glucocorticoids on fetal cardiac metabolism and function, and the transition at birth, 2) effects of exposure to Triclosan (an antibacterial in many soaps), and 3) alterations in the maternal microbiome. The laboratory uses a combination of in vivo techniques, including use of telemetry to measure fetal cardiovascular function in utero, biochemical techniques, and systems biology methods- both transcriptomics and metabolomics.
Department:
Medicine
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/10/2021 10:37:46 AM
Research Description
The research in Dr. Khemtong’s group is focused on understanding intermediary metabolism using stable isotope tracers, primarily carbon-13, combined with magnetic resonance and mass spectrometry techniques. His group is also working on real-time imaging of metabolic processes using hyperpolarized carbon-13 MRI.
Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/19/2019 9:44:16 AM
Research Description
Mammalian cell culture systems. Epigenetic regulation of transcription; chromatin structure and function; epigenetic silencing of tumor suppressor genes in cancer; single-molecule analysis of chromatin structure
Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/30/2020
Research Description
Development, Implementation and Evaluation of a variety of research-aligned programs linking UF research faculty and graduate students with precollege science teachers, talented high school students, and underserved schools and communities across Florida
Department:
Periodontology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/9/2021
Research Description
Role of dominant microRNAs in periodontal disease (Current new Funded study). Major interests are to examine the role of major periodontal pathogens causal association with systemic diseases including Alzheimer’s disease, atherosclerosis, and rheumatoid arthritis.
Department:
Aging & Geriatrics Research
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/9/2021 3:06:42 PM
Research Description
Physiology, biology & biochemistry of aging, with focus on mitochondrial biology, autophagy, apoptosis, oxidative stress, anti-aging interventions and translation to clinical trials based on findings from pre-clinical models.
Department:
Medicinal Chemistry
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/10/2021 4:34:04 PM
Research Description
Li’s scholarly interests range from organic chemistry, biochemistry, medicinal chemistry to physical chemistry, computational chemistry, molecular biophysics and pharmacology. His research focuses on molecular recognition, with a strong application to structure-based drug dresign, especially for anti-cancer and neurodegenerative diseases.
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/16/2020
Research Description
Jonathan D. Licht, MD, is the Director of the University of Florida Health Cancer Center, Dr. Licht's laboratory studies aberrant epigenetics and gene regulation as a cause of hematological and other malignancies
Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/9/2021 4:49:08 PM
Research Description
Cerebral metabolism; development of methods to measure metabolism in vivo; protein regulation of biofilm formation; Interaction of proteins and membanes in regulating cell membrane biophysics; nuclear magnetic resonance (NMR)
Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/10/2021 8:46:40 AM
Research Description
Epigenetic and metabolic regulation of tumor progression and therapeutic resistance.
Department:
Neuroscience
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/20/2020
Research Description
Application of gene transfer to study animal models of neurodegenerative disorders including Parkinson's disease, Huntington's disease, brain tumors, and ischemia.
Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/10/2021 10:29:25 AM
Research Description
The study of central nervous system structure and function with magnetic resonance. In particular, mapping of brain structural connectivity using diffusion-weighted magnetic resonance imaging methods and investigating the mechanism of memory modulation with electrical stimulation.
Department:
Environmental Health
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/9/2021 3:05:20 PM
Research Description
Pathogenic mechanisms of Shigella and Chlamydia Evolution and emergence of Shiga toxin-producing Shigella flexneri Cell wall metabolism and cell division processes of Chlamydia spp. Surveillance of non-HIV sexually transmitted infections in Haiti Laboratory capacity building
Department:
Molecular Genetics & Microbiology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/30/2020
Research Description
Focused on the use of statistical theory to elucidate the relationship between genotype and phenotype. Currently interested in integration of omic data.
Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/16/2020
Research Description
Multidisciplinary approaches: including molecular biology, biophysical techniques, structural biology (cryo-EM and crystallography), and kinetics are used to study biological molecules (viruses and proteins)
Department:
Infectious Diseases and Immunology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/30/2020
Research Description
Host and viral protein interactions relevant to therapeutic and vaccine development, Retrovirus vector for gene transfer based on foamy virus.
Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/10/2021 3:54:09 PM
Research Description
The Merritt lab is dedicated to understanding intermediary metabolism through the process of measuring metabolic flux quantitatively in living systems, including cell culture, perfused organs, and in whole animal models. Our preferred method of measuring flux is with nuclear magnetic resonance (NMR), which provides unique insights into biochemistry due to its extreme sensitivity to changes in chemical bonding. Our primary target of study is the citric acid cycle (CAC), which is the first stage of ATP production from nutrients. Flux through the CAC has been shown to be up- or downregulated in a variety of pathophysiological states. In addition, the CAC generates a variety of intermediates that are used in biosynthesis and can also serve as a “recycler” of carbon skeletons generated by processes like autophagy. While NMR is information rich, it is also characterized by poor absolute sensitivity. The other arm of my research group includes developing hardware that amplifies magnetic resonance signals, improving sensitivity and enabling a variety a new flux measurements in vivo. These methods are known collectively as “hyperpolarization”.
Department:
Infectious Diseases and Immunology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/15/2020
Research Description
Intestinal disorders (IBD, colon cancer) and infectious diseases transcriptomic and metabolic machinery of intestinal innate and T cells during steady state and intestinal infection
Department:
Anatomy & Cell Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/16/2020
Research Description
Development of novel therapy for colorectal and breast cancers.
Department:
Oral Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/30/2020
Research Description
My main research projects focus on investigating the relationship between oral alkali production from arginine and dental caries experience in children and adults.
Department:
Neuroscience
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/30/2020
Research Description
Our research focuses on understanding the underlying molecular mechanisms controlling gene expression in the inflammatory response and in the etiology of Type 1 Diabetes.
Department:
Biomedical Engineering
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/26/2017 12:45:56 PM
Research Description
Studies how stem cell strategies could be used to repair the brain. We use the hippocampus as a model to understand how make the brain receptive to neuron addition because the hippocampus adds new neurons throughout life in all mammals, including humans
Department:
Pathology, Immunology & Laboratory Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/15/2020
Research Description
Immune recognition, structural biology and drug discovery; cancer research; immunological regulation by T cells; structural interactions defined by X-ray crystallography and functional studies; drugs to prevent and treat COVID-19 .
Department:
Pediatrics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/25/2019 1:47:12 PM
Research Description
Various stem cell (i.e. bone marrow, fetal, iPSCsand hepatic) biology and how they can be used as a tool in gene therapy or in their participation in liver regeneration. Also looking into how hepatic cells (hepatocytes, ductular cells, stellate cells) can be used in developing a bio-artificial liver device (BAL), bioengineering
Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/22/2015
Research Description
Neuronal cytoskeletal proteins especially microtubules, microfilaments and their associated proteins. Enzyme catalysis and regulation.
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/9/2021 3:11:41 PM
Research Description
The long-term goal of my research is to understand the mechanisms that underlie the development of blood cancers with a focus on studying the genetic pathways that control the proliferation, survival and self-renewal of normal or leukemic hematopoietic stem cells. The current main research focuses: 1. Molecular regulation of normal hematopoietic stem cell (HSC) and its leukemic transformation 2. The role of the Wnt/beta-catenin signaling in the development and maintenance of myeloid neoplasms 3. Transcriptional, epigenetic and epitranscriptomic regulation of normal hematopoiesis and leukemogenesis 4. Development of targeted therapies for myeloid malignant diseases
Department:
Pediatrics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/28/2018
Research Description
Dr. Rivkees’ laboratory is currently focusing on the role of adenosine on cardiac development and the fetal programming of adult cardiac disease via epigenetic mechanisms. In addition, we are studying developmental brain injury, focusing on white matter injury and oligodendrocyte biology.
Department:
Pathology, Immunology & Laboratory Medicine
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/15/2021 2:03:34 PM
Research Description
Molecular evolution of viruses, with special emphasis on HIV/SIV and SARS-CoV-2. Development and application of new bioinformatics and phylogenetic analysis tools to investigate the molecular epidemiology of microbial pathogens, with emphasis on RNA-virus
Department:
Physiology & Functional Genomics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/10/2021 10:18:56 AM
Research Description
Cellular and biochemical mechanisms by which G protein-coupled receptors activate physiologically important tyrosine kinase signaling pathways.
Department:
Whitney Laboratories
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/14/2021 3:39:49 PM
Research Description
Research focus:the cellular and molecular mechanisms of development and regeneration in annelids and other closely related marine animals. Interests: patterning of embryonic stem cells, neurogenesis, regenerative biology and patterning of the germline.
Department:
Aging & Geriatrics Research
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/14/2021 4:37:53 PM
Research Description
Molecular mechanisms underlying inner ear aging, cellular detoxification, and sex difference in aging using mice as a model system
Department:
Pediatrics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/10/2021 2:14:35 PM
Research Description
For four decades, Dr. Srivastava’s research has been focused on the following two parvoviruses, the non-pathogenic adeno-associated virus (AAV), and a common human pathogen, the parvovirus B19, and the development of recombinant parvovirus vectors. The current emphasis is on gene therapy of hemophilia, and other liver diseases, and genome editing for beta-thalassemia and sickle cell disease
Department:
Oral Biology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/10/2021 9:54:43 AM
Research Description
Pathogenesis of oncogenic herpesviruses, epigenetic regulation of gammaherpesvirus infection, regulation of viral latency and lytic activation, coronavirus infection
Department:
Molecular Genetics & Microbiology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/10/2021 8:02:36 AM
Research Description
Mutation and analysis of human disease and susceptibility genes.
Department:
Physiology & Functional Genomics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/14/2021 4:14:36 PM
Research Description
Measurement of skeletal and cardiac muscle physiology, function, and metabolism using innovative NMR and MRI based techniques. Studies the effect of gene transfer/pharmacological correction from the basic cell level to humans with muscular dystrophies.
Department:
Molecular Genetics & Microbiology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/16/2021
Research Description
We study microsatellite repeat expansion diseases, including myotonic dystrophy. We use molecular, cellular, computational, and animal-based approaches to understand basic mechanisms that cause symptoms in this and related multi-systemic diseases, as well as identify treatments that will help patients. We also study RNA localization at a basic level, to understand why and how RNA molecules move to different places in the cell. We seek to combine high-throughput genomics approaches with single molecule imaging approaches to characterize and understand this new frontier in biology.
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/10/2021 8:44:59 AM
Research Description
Aldosterone action & hyperaldosteronism, renal endothelin action, hypertension, ion transporting ATPases; K+ channels; signal transduction.
Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
No
Last Updated
6/15/2021 2:02:12 PM
Research Description
The Xie Lab’s research interest is to decipher biogenesis pathways that generate RNAs essential for gene expression in metazoans and associated Herpesviruses. Our current focus is on microRNAs, small non-coding RNA molecules that control the function of other genes. In the near future, we will integrate approaches from biochemistry, cell biology, virology and bioinformatics to study viral and cellular non-canonical microRNA biogenesis pathways, which surprisingly incorporate several fundamental cellular machineries involved in processing other classes of RNAs. Our efforts will provide a better basis for developing novel therapeutics that alter microRNA levels to combat a variety of diseases, including Herpesvirus-induced malignancies and other cancers.
Department:
Surgery
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
5/26/2021
Research Description
Department:
Pediatrics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/10/2021 4:10:49 PM
Research Description
AAV vector design. AAV vector production.

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