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Department:
Neurology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/15/2020
Research Description
Dr. Farrer's research is to predict and prevent Parkinson’s disease through a combination of human genetic analyses, molecular genetic engineering and neuronal biology, mouse modeling, brain slice electrophysiology and pharmacology. He directs the Parkinson’s Research Laboratory. Dr. Farrer also directs the Clinical Genomics Program for UF Health that seeks to improve health outcomes for patients by generating and interrogating genomic data, to accelerate diagnosis and target treatments more appropriately.
Department:
Neuroscience
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/15/2020
Research Description
Dr. Abisambra established a vigorous research program concerning fundamental biological processes critical to neuronal function that are based on RNA translation and ribosomal health. He is working together with UF faculty on translational research programs related to neurodegenerative disorders, including Alzheimer’s disease, traumatic brain injury, and fronto-temporal dementia, among 24 other tauopathies. He has secured extramural grant funding to support his research. He is teaching and mentoring graduate students.
Department:
Whitney Laboratories
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/15/2017 12:39:53 PM
Research Description
Chemical senses, sensory physiology, invertebrate neurobiology.
Department:
Neuroscience
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/15/2020
Research Description
Dr. Alviña is developing a vigorous research program investigating how neurons integrate synaptic inputs and how behavioral states affect normal neuronal processing. Areas of focus for her research include studies of synaptic transmission in brain regions important for learning and memory, and the impact of environmental factors, including stress, on these processes. Her laboratory utilizes a multi-disciplinary approach that includes behavioral analysis, electrophysiology, and neuropharmacology.
Department:
Otolaryngology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/30/2020
Research Description
Hearing loss and facial paralysis: prevention and treatment
Department:
Ophthalmology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
3/17/2020
Research Description
Research is focused on mechanisms of inherited retinal degeneration and neuroprotection. His most recent studies have shown the important contribution of endogenously expressed cytokines such as leukemia inhibitory factor (LIF)
Department:
Neuroscience
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
7/12/2017
Research Description
My lab is focused on elucidating the mechanisms involved in the onset and propagation of neurodegenerative diseases. Over the last decade, a number of studies have implicated a prion-like mechanism for the accumulation and dissemination of proteins involved in Alzheimer’s Disease, Parkinson’s Disease, and Amyotrophic Lateral Sclerosis (ALS), among others. Taking a page from studies performed in the prion field, we have used both cell and animal models of these disorders to reveal that similar to the prion protein, these toxic misfolded proteins can template their structure onto natively folded proteins, thereby causing an accumulation of pathological inclusions. Additionally, we have demonstrated the ability for misfolded proteins implicated in ALS and Parkinson’s Disease to propagate throughout the central nervous system along known neuroanatomical pathways, most likely via axonal connections. By better understanding these properties, our hope is to develop therapies to prevent and/or stop the spread of these debilitating diseases.
Department:
Neuroscience
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/29/2017 12:34:28 PM
Research Description
Molecular mechanisms of age related cognitive decline
Department:
Neuroscience
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/23/2020
Research Description
Develop technology and application of magnetic resource imaging and spectroscopy.
Department:
Molecular Genetics & Microbiology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/16/2020
Research Description
Molecular pathogenesis of the herpesviruses; role of long non-coding RNAs and miRNAs on latency and reactivation; development of novel therapeutics to disrupt HSV latency and block recurrent disease.
Department:
Physiological Sciences
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
7/8/2019
Research Description
A variety of neuromuscular diseases result in impaired cough (dystussia) and/or impaired swallow function (dysphagia). Cough and swallows are controlled by complex brainstem networks which, until recently, have been studied in isolation. However, in neuro
Department:
Neuroscience
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
No
Last Updated
6/16/2020
Research Description
My lab uses transgenic & knockout mouse models, and cell models, to determine molecular mechanisms by which mutations in specific genes cause familial neurodegenerative diseases - primarily Alzheimer's disease and amyotrophic lateral sclerosis.
Department:
Physiological Sciences
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/23/2020
Research Description
Understanding the molecular-physiological-through-behavioral neurobiology of motor, sensory and cognitive plasticity following pharmacotherapy and neurorehabilitation using preclinical (rodent) models of neurotrauma (spinal cord, traumatic brain injuries, stroke) and neurodegenerative diseases.
Department:
Pediatrics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/16/2020
Research Description
Optimizing gene therapy vectors (AAV) for the treatment of inherited retinal disease.
Department:
Psychiatry
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/22/2015
Research Description
Drug addiction is a chronic disorder that is characterized by compulsive drug taking and relapse after periods of abstinence. The research in our laboratory focuses on the development of non-addictive treatments for nicotine, alcohol, and opioid addiction
Department:
Neuroscience
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/15/2020
Research Description
The principal aim of my research is to investigate how medial temporal lobe and frontal cortical structures involved in memory and high-level sensory perception are altered by advanced age and how nutrition can circumvent possible network impairments.
Department:
Neuroscience
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/15/2020
Research Description
Research involves studies on neuroinflammatory mechanisms of blood-brain barrier disruption in ischemic stroke
Department:
Oral Surgery
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/23/2020
Research Description
Molecular processes that lead to the establishment of chronic pain; alterations in function of the N-Methyl-D-Aspartate (NMDA) receptor and vanilloid receptor as a result of persistent peripheral stimulation.
Department:
Neuroscience
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/23/2020
Research Description
The focus of my studies is to characterize how innate immune signaling modifies disease pathology and neurodegeneration in mouse models of neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease and ALS.
Department:
Pediatrics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/16/2020
Research Description
Dr. Vijay Chandran’s research and clinical interests concern the causes and treatment of neural repair and neurodegenerative diseases. His research focuses on how the nervous system works and how it responds and repairs itself due to the damage caused by injury or disease. Our two main goals are to: (1) Discover strategies for enhancing neuronal regrowth and staling neuronal loss after injury. (2) Understand the nervous system response and recovery during damage caused by disease. A unique feature of our lab is that we are focusing on integrating various omics techniques with basic neurobiology and systems analyses to develop a more systematic understanding of nerve injury and neurodegenerative conditions. Our long term research interest involves identification of the molecular mechanism responsible for neural repair and neuronal degeneration.
Department:
Pediatrics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
8/8/2017 11:51:25 AM
Research Description
We are interested in how the cerebral cortex is modified by experience and how early insults and/or injuries disrupt this process both acutely and long-term. Currently, we are are studying two mouse models to address these issues: 1) A mouse model of diffuse white matter (and gray matter) injury in premature infants, and 2) manipulation of thyroid hormone levels during fetal and neonatal brain development. We use the mouse primary visual cortex as our model system and employ techniques that allow us to attack our research questions from the level of molecules to behavior. Prominent techniques include quantitative and in situ analyses of gene expression, in vivo electrophysiology, in vivo two-photon imaging (calcium signals and neuronal structure), immunofluorescence and neuroanatomical approaches, and behavioral testing.
Department:
Oral Surgery
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/23/2020
Research Description
Cellular and Molecular Pain Research Using Whole Cell Patch Clamp Techniques in Rat DRG
Department:
Physiology & Functional Genomics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/15/2020
Research Description
The overarching focus of my research is to understand mechanisms of induced plasticity and to couple neuroplasticity with CNS repair. My primary focus is on spinal cord injury and the spinal networks controlling breathing. I have extensive expertise in in vivo whole nerve recording, plethysmography, electromyography, spinal cord stimulation, immunohistochemistry, in vivo RNA interference, and stem cell/olfactory ensheathing cell transplantation, which I want to apply to the investigation of such therapeutic strategies as neuromodulation, neurotransplantation, and neurotrophin-based repair and rehabilitation.
Department:
Physiological Sciences
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/16/2020
Research Description
The neural mechanisms of behavioral and reflex control of breathing. Respiratory sensation mechanisms in various patient populations. Cortical control of breathing. Respiratory rehabilitation in patients with lung disease, stroke, neuromuscular disease an
Department:
Neurology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/23/2020
Research Description
Dr. DeKosky's interests have been in basic, clinical, and translational research, centered on genetics, neuropsychiatric manifestations, neuroimaging and therapeutic trials to treat and prevent Alzheimer’s disease, age related memory loss, and traumatic brain injury. He is available tor assistance in clinical studies.
Department:
Neurosurgery
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/15/2020
Research Description
Investigate the role of stem/precursor cells in normal brain function and in states of injury and disease such as cancer. Developing and enabling innovative technologies to identify and measure stem cell and cancer stem cell activity and explore new treatment strategies leading to translational therapeutic development.
Department:
Psychology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
5/31/2016 9:17:21 AM
Research Description
Neurobiology of autism spectrum disorder; neurobiology of self-injurious behaviors.
Department:
Ophthalmology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/16/2020
Research Description
Dr. Dinculescu received her Ph.D. in Biochemistry from University of Florida in 2002. Her research is focused on understanding the molecular mechanisms in several retinal degeneration disorders, including Usher syndrome. The ultimate goal is to develop therapeutic strategies to prevent the loss of sight caused by these disorders. Usher syndrome type III (USH3A), an autosomal recessive disorder, is caused by mutations in Clarin-1 (CLRN1) protein, leading to combined vision and hearing loss. The main goal of this project is to understand the function of CLRN1 in the retina, identify its binding partners, and its cellular localization pattern. This information will be used to develop a rational treatment for the USH3A disorder. She is also interested in protein aggregation mechanisms leading to the formation of extracellular deposits associated with vision loss in age-related macular degeneration, a major cause of blindness in the elderly population.
Department:
Biomedical Engineering
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
7/24/2017
Research Description
Areas of current research activity include the following: (1) multimodal neuroimaging, (2) neuronal oscillations, (3) neuronal network analysis, and (4) cognitive neuroscience and cognitive impairments
Department:
Anesthesiology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/16/2020
Research Description
Investigation of the clinically relevant anti-oxidant and anti-inflammatory drugs using in vivo preclinical models and human biospecimens of ischemic and hemorrhagic strokes, traumatic brain injury, Alzheimer, and other neurological disorders
Department:
Pediatrics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/16/2020
Research Description
The phenomenon of genomic imprinting is the differential modification of the maternal and paternal genetic contributions to the zygote, resulting in the differential expression of parental alleles during development and in the adult. A disturbance in genomic imprinting has been found to cause several human diseases including Prader-Willi and Angelman syndromes.
Department:
Pediatrics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/11/2018 3:04:49 PM
Research Description
Our laboratory focuses on two distinct but unified research concentrations. These areas include 1) gene therapy for monogenic disease that affect the normal function of motor neurons and skeletal muscle and 2) incorporation of optogenetics to enhance rehabilitation of the neuromuscular system following nerve or spinal cord injury. Optogenetics is a tool that allows one to activate cells in live animals upon exposure to a LED light source.
Department:
Psychiatry
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/23/2020
Research Description
Our work focuses on using neuroimaging of functional brain activity and white matter connectivity in mouse models of Alzheimer's disease. Specifically, our laboratory is interested in understanding the in vivo functional and microstructural changes that occur in the brain as a result of amyloidosis, tauopathy, and altered CNS inflammation.
Department:
Neurosurgery
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
9/26/2016
Research Description
Dr. Flores joined the University of Florida faculty to become part of the Preston A. Wells Jr. Center for Brain Tumor Therapy in order to focus on developing novel approaches to target brain tumors. She has developed a pre-clinical platform that utilizes tumor-specific autologous immune cells to efficiently target intracranial tumors. Her research interests are primarily in determining biological interactions between various cellular compartments involved in adoptive immunotherapy. Her studies also focus on leveraging systemic toxicity of frequently practiced clinical treatments in order to further enhance anti-tumor efficacy of immunotherapy.
Department:
Neuroscience
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/11/2018 9:33:40 AM
Research Description
Brain aging from the epigenetic and physiological level to cognitive level. Students acquire skills in molecular or electrophysiological techniques to examination the influence of environmental and lifestyle factors on epigenetic regulation of gene transcription and synaptic plasticity mechanisms involved in memory.
Department:
Pharmacodynamics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
5/26/2016
Research Description
Neurophysiological mechanisms related to stress, aging, memory, epilepsy, and drug abuse.
Department:
Neuroscience
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/16/2020
Research Description
Understanding the cellular pathways and molecular interactions involved as underlying causes of neurodegenerative diseases, with special emphasis on Parkinsons disease.
Department:
Neuroscience
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/22/2015
Research Description
Pathogenesis and treatment of Alzheimers and other Neurodegenerative disease
Department:
Biomedical Engineering
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/30/2020
Research Description
Dr. Gunduz' research is focused on finding precursors to behavior and aftereffects of stimulation in neural networks through electrophysiology and bioimaging. Her lab aims to translate this knowledge into clinical diagnostic and therapeutic systems to improve quality of life of those suffering from neurological disorders. To this end, Dr. Gunduz works with many clinical populations, such as neurosurgical patients with epilepsy and movement disorders (Tourette’s syndrome, Parkinson’s Disease), as well as stroke patients undergoing neurorehabilitation.
Department:
Pharmacology & Therapeutics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/16/2020
Research Description
Brain tumor immunotherapy. Chemokines and chemokine receptors in glioma. Focus on glioblastoma and pharmacological targeting using pre-clinical animal models
Department:
Physiological Sciences
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/15/2020
Research Description
Cardiovascular neurophysiology and neural mechanisms underlying hypertension.
Department:
Neuroscience
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/15/2020
Research Description
Interactions of neurotrophic factors, apoptosis-related genes, and antioxidants in fetal alcohol syndrome
Department:
Center for Movement Disorders and Neurorestoration
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/15/2020
Research Description
His current research interests involve the use of non-invasive neuromodulation in movement disorders to study network connectivity in Parkinson’s disease and the use of wearable technologies in clinical care and research.
Department:
Psychiatry
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
7/8/2019
Research Description
1. Gene therapy using recombinant adeno-associated virus-based vectors for the treatment of brain and thyroid disorders 2. Parvovirus-host interactions
Department:
Pediatrics
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/16/2020
Research Description
My research group investigates immune modulation and tolerance induction using adeno-associated virus (AAV) gene therapy. We are currently developing an AAV gene immunotherapy that is capable of selectively inducing of antigen-specific regulatory T-cells (Tregs) as a means to treat/reverse autoimmune disease.
Department:
Neurosurgery
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
No
Last Updated
6/16/2020
Research Description
1. Study the inflammatory healing response in aneurysms and develop novel tissue-engineered treatments and devices for aneurysms, 2. Study the inflammatory pathways that lead to the development of cerebral aneurysms in a flow-chamber model as well as in vivo animal models
Department:
Neurology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/1/2016
Research Description
A majority of Dr. Jaffee's research has focused on traumatic brain injury and utilizing a multidisciplinary approach to developmental strategies for assessment and management. Dr. Jaffee has personal experience with initiatives to better understand blast injury and has an interest in studying long-term sequelae of traumatic brain injury and concussion. Dr. Jaffee also has an interest in the interface between neurologic disease and psychiatric symptoms and the interface between neurology and sleep.
Department:
Neuroscience
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/15/2020
Research Description
Focuses on behavioral development, cognitive function and decline in mouse models of neurodegenerative disorders and neural mechanisms underlying dementia.
Department:
Physiological Sciences
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/16/2020
Research Description
In vivo/in vitro electrophysiology, neurotracing, and immunohistochemical phenotyping of the visceral and somatic sensory neurons, spinal cord and brainstem interneurons, and motoneurons; role in peripheral nerve/spinal cord injury and visceral disease (diabetes, hypertension), and chronic deep tissue pain. New grants are on neuromodulation of visceral nerves with novel implanted neurostimulation devices.
Department:
Electrical and Computer Engineering
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
7/6/2017
Research Description
Dr. Judy’s research involves the development and use of state-of-the-art engineering technologies to advance fundamental neuroscientific understanding and to create effective neurological therapies. A particular focus of his research in on advance neural interfaces for acute and chronic applications as well as wearable sensing systems.
Department:
Pediatrics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/15/2020
Research Description
Dr. Kang’s laboratory focuses on the genetics of muscular dystrophy and the pathogenesis of disease in MEGF10 myopathy. Ultimately, these studies are expected to help identify novel therapeutic strategies for these diseases.
Department:
Pharmacodynamics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
7/5/2019 8:49:20 AM
Research Description
My research interests are the adaptations in endocrine and cardiovascular systems in pregnancy and at birth. The current focus of my research is fetal and neonatal metabolism, including 1)the effect of glucocorticoids on fetal cardiac metabolism and function, and the transition at birth, 2) effects of exposure to Triclosan (an antibacterial in many soaps), and 3) alterations in the maternal microbiome. The laboratory uses a combination of in vivo techniques, including use of telemetry to measure fetal cardiovascular function in utero, biochemical techniques, and systems biology methods- both transcriptomics and metabolomics.
Department:
Neuroscience
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/15/2020
Research Description
Dysregulation of dopamine transmission is involved in Parkinson’s Disease, drug addiction, compulsivity and altered peripheral immunity. Our research is focused on studying how changes in the peripheral immunity affect dopamine transmission in the central nervous system.
Department:
Pharmacodynamics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/26/2019 3:39:53 PM
Research Description
The Krause laboratory uses genetically modified mice to identify neuronal circuits that promote susceptibility or resiliency to stress-related disease.

Damon G. Lamb, Ph.D.

Department:
Psychiatry
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/16/2020
Research Description
He is interested in the complex interaction of autonomics, emotional function and cognition. He conducts clinical-translational research and education in human neuroimaging of psychiatric and related disorders using magnetic resonance imaging and spectroscopy, human electrophysiology, and computational neuroscience. Prospective students should have strong quantitative and computational skills.
Department:
Neuroscience
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/30/2020
Research Description
My research involves generation of anti-amyloid beta peptide single-chain variable fragments and administrating them to various neurodegenerative disease animal models via Adeno-Associated virus mediated gene transfer. I have cloned light and heavy chain units from several anti-Abeta, anti-tau, anti-alpha-synuclein antibodies available in the laboratory and nstructed a single chain Fv. Using a novel technique of AAV-mediated gene delivery into eonatal brain I express these scFv in transgenic mice in an attempt to attenuate amyloid deposition. Additionally, I am working on development of anti-generic amyloid single-chain fragments directed specifically against fibrillar Amyloid beta. For several years we have been attempting to dissect potential mechanisms involved in Abeta vaccination strategies for the therapy of AD using ransgenic mouse models. Recently we provided a framework to evaluate proposed mechanisms of Abeta attenuation mediated by peripheral administration of an anti-Abeta monoclonal antibody (mAb) effective in passive immunization paradigm. The data suggests that the mAbs are either indirectly enhancing clearance of Abeta or targeting a low abundance aggregation intermediate. Another path of research that I am pursuing is testing a new strategy to develop animal models that more closely resemble Alzheimer’s disease processes in the human brain. I will test the utility of a novel mechanism to deliver individual beta-amyloid protein fragments as well as other non-Abeta amyloidogenic peptides torodent brain and determine whether these models develop a brain pathology that closely resembles Alzheimer’s.
Department:
Neuroscience
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
No
Last Updated
6/16/2020
Research Description
In vivo modeling and therapeutics for neurodegenerative diseases (ALS, AD, PD, FTD)
Department:
Psychiatry
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/15/2020
Research Description
Broadly, Dr. Lewis’ research interests include understanding the neurobehavioral concomitants of chronic and acute substance use. Although his past/recent analyses have included opioids, marijuana, and other substances of abuse, he has maintained a particular focus on alcohol. This interest spans all patterns of consumption, from moderate/low-risk to chronic/heavy drinking, and has included investigations across the lifespan, from fetal exposure to elderly drinkers.
Department:
Psychiatry
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/30/2020
Research Description
Our lab studies the abnormal repetitive behavior diagnostic for autism and common in neurodevelopmental disorders. We employ mouse models to study the development and neurobiological basis of repetitive behavior using behavioral, pharmacological, biochemi
Department:
Neurology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/16/2020
Research Description
Dr. Li’s research is mainly focused on the pathophysiology and experimental therapeutics of dystonia, restless legs syndrome, ALS/FTD. He is also broadly interested in animal models of movement disorders and molecular and cellular mechanisms of synaptic plasticity during development and adult learning and memory.

Yijun Liu, Ph.D.

Department:
Psychiatry
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/22/2015
Research Description
Functional neuroimaging study of obesity, aging, brain injury and neuropsychiatric disorders.
Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/30/2020
Research Description
Cerebral metabolism; development of methods to measure metabolism in vivo; protein regulation of biofilm formation; Interaction of proteins and membanes in regulating cell membrane biophysics; nuclear magnetic resonance (NMR)
Department:
Pediatrics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/25/2019
Research Description
The research in my lab is focus on developing new therapies of lysosomal storage diseases (LSDs) based on the understanding of molecular mechanisms of the pathogenesis of these diseases. These inherited metabolic conditions are caused by defects in a wide spectrum of lysosomal and a few non-lysosomal proteins resulting in accumulation of undigested substrates, resulting in dysfunction of lysosomal/endosomal system. The almost 60 different LSDs are individually rare genetic conditions, but, collectively, the incidence is approximately 1/2,000-3,000 live births. Since lysosomal/endosomal system is essential for cell homeostasis, this “inborn organelle disorders” results in multi-systemic diseases, and predominantly affecting the brain. The study LSDs allowed the discovery of several biological processes including the discovery of mannose-6-phosphate targeting system and currently gives insights into neurodegenerative mechanism in Alzheimer and Parkinson’s diseases. In LSDs, the development of clinical symptoms usually correlates with a level of residual deficient enzyme activity. In patients with late onset forms of LSDs, a residual lysosomal activity is a result of missense mutations, which partially preserves catalytic enzyme function but mostly impairs the early folding process in the ER. These mutant lysosomal enzymes do not reach its appropriate conformation, and subsequently are directed to ER-associate degradation (ERAD) pathway, and are ultimately degraded by the ubiquitin-proteosome system. In this context, small molecule therapeutics are an attractive approach to treat LSDs. Enzyme-enhancement agents, including pharmacological chaperones (PC), are small molecules which are able to assist a mutant misfolded protein to achieve a native-like conformation in the endoplasmic reticulum (ER), allowing it to escape the ERAD pathway, and reach the lysosome. An advantage of this approach is that small molecules are much more likely to cross the blood brain barrier and reach neuronal cells, which are dramatically affected in LSDs. In addition, principles learned in treating one type of LSD can be applied not only to other LSDs, but also to other misconformation protein diseases, which is also feature of common neurodegenerative conditions.
Department:
Neuroscience
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/20/2020
Research Description
Application of gene transfer to study animal models of neurodegenerative disorders including Parkinson's disease, Huntington's disease, brain tumors, and ischemia.
Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/25/2019 11:19:51 AM
Research Description
The study of central nervous system structure and function with magnetic resonance. In particular, mapping of brain structural connectivity using diffusion-weighted magnetic resonance imaging methods and investigating the mechanism of memory modulation with transcranial electric current stimulation.

Mark Q. Martindale, Ph.D.

Department:
Whitney Laboratories
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/16/2020
Research Description
Director of the Whitney Laboratory for Marine Bioscience. His research focus is aimed at elucidating the cellular and molecular basis for the evolution of cell-type complexity, regenerative biology, and cellular engineering.
Department:
Physiological Sciences
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/30/2020
Research Description
neurotoxicology, Parkinson's disease, environmental exposures, transcriptomics, proteomics, zebrafish
Department:
Anesthesiology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/30/2020
Research Description
Mechanisms of intergenerational neurocognitive abnormalities induced by parental exposure to general anesthesia
Department:
Psychiatry
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/15/2020
Research Description
Our group studies how genes, environment, and culture interact to influence human emotion and behavior. In particular, we focus on how these factors affect the development and expression of neuropsychiatric syndromes, including anxiety, resilience, ADHD, OCD, compulsive hoarding, and tic disorders. Approaches include neuropsychological, electrophysiological, and physiological approaches, as well as functional neuroimaging.
Department:
Neuroscience
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
7/5/2019
Research Description
Oscillations are prominent in all realms of the physical and biological world. Clocks tick, fire flies flash and neurons of the brain ‘fire’ action potentials. While it is known that two clocks on a wall will synchronize their pendulums and specific species of fire flies will phase lock their flashes, the basic mechanisms of how large populations of neurons interact in a coordinated manner to enable a rich repertoire of adaptive behaviors is relatively unknown. Specifically, we have a limited understanding on how neurons self-organize their activity to produce the synchrony that is needed to transfer information across large-scale neural networks. Moreover, even less is known regarding how information is transformed and updated as it propagates across the brain. Theoretically, it is the oscillatory rhythms of the brain, along with the synaptic architecture, that allow neurons to transiently synchronize and desynchronize their activity, optimizing nimble computations at the “speed of thought”. Fortunately, we have reached a technological threshold that has permitted the testing of theoretical models on large amounts of neural data. Therefore, my research seeks to understand how the brain, a densely interconnected set of individual neurons, rapidly translates environmental information into complex representations in support of cognitive function. In order to achieve these goals, my collaborators and I have embarked on a unique research trajectory that will allow us to test the hypotheses of complex network activity using both a bottom-up approach, inspired by computational models, and a top-down approach, re-evaluating our data in the perspective of non-linear physics. It is our expectation that, by adopting an integrative approach that bridges disciplines, we can learn how the small actions of single neurons, connected in a network can bring about the emergence of sophisticated dynamics that support behavior and higher cognitive function. Moreover, by examining neural processing on multiple scales, from small groups of isolated cells to the population dynamics of entire brain regions, we believe that we will find a common etiology of how coordinated activity emerges that can be extended into the larger field of complexity.” “We also have a research track investigating the changes in neuronal dynamics behind age-related decline in memory and cognition. Along with my collaborators in McKnight Brain Institute in the Age-Related Memory Loss group, we seek to find therapeutic interventions that maximize longevity and neuronal processing in hopes of maintaining independence in the elderly population.
Department:
Neurology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/15/2020
Research Description
My research focuses on understanding the pathological mechanisms of Parkinson disease and related disorders, and in particular the role that abnormal protein accumulation, such alpha synuclein, plays in these disorders.
Department:
Neuroscience
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/28/2018
Research Description
The McIntyre Lab is broadly interested in the molecular mechanisms that underlie olfactory function. We study both the sensory neurons in the nasal cavity that detect odors in the environment as well as the neurons in the olfactory bulb that begin the neural processing of this information. The lab currently has several ongoing projects. First, we are applying gene therapy approaches to correct congenital defects in the sense of smell. Currently we are focused on mutations affecting ion channel function. We are developing methods to delivery and re-express functional copies of these channels to the olfactory epithelium to restore olfactory function. To evaluate the effectiveness of these therapies we used immunofluorescence, calcium imaging, electrophysiology and behavioral experiments. In the olfactory bulb, we are studying how physiological conditions affects odor processing. Input into the olfactory bulb from higher regions of the brain are known to modulate how neurons in the bulb respond to odors, making them more or less responsive. We are investigating neuromodulators involved in hunger/satiety signaling and those that change with aging. Our work focuses on several GPCRs involved in these signaling pathways that localize to the primary cilia that project from neuronal cell bodies. Cilia are critical for cellular function, and disruptions of cilia function can lead to numerous disease phenotypes. The lab is working to further understand the role of cilia in integrating a variety of signals and the modulation of neuronal processes. To achieve these goals, we have developed several new mouse models to look at cell specific ablation of cilia and immunofluorescence and confocal microscopy, calcium imaging, electrophysiology, molecular biology and behavior.
Department:
Neurosurgery
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
7/9/2019
Research Description
Immunotherapy of adult and pediatric brain tumors. Mechanisms of resistance in brain tumors to immunologic rejection. Combinatorial therapeutics involving chemotherapy, radiation, and immunotherapy
Department:
Physical Therapy
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/16/2020
Research Description
We focus on cellular mechanisms of spinal respiratory (and non-respiratory) motor plasticity following intermittent exposure to low oxygen (intermittent hypoxia). We investigate mechanisms at the cellular through whole animal levels, and actively explore the ability to harness intermittent hypoxia as a treatment to improve respiratory and non-respiratory motor function in rodent models of chronic spinal injury and ALS. In multiple collaborations, we also test the potential of intermittent hypoxia to enhance function in normal humans, and to treat those with chronic disease or spinal injury.
Department:
Whitney Laboratories
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/20/2019 11:50:20 AM
Research Description
Genomic Bases of Memory and Neuronal Evolution. Our laboratory works to characterize basic mechanisms underlying the design of nervous systems and the evolution of neuronal signaling mechanisms. The major questions are: (1) why are individual neurons so different? (2) How do learning and memory store in neuronal genomes and neural circuits? (3) How to restore memories? (4) How to make “better” neurons and brains and improve cognitive functions?
Department:
Pharmacology & Therapeutics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/11/2018
Research Description
We use molecular biological, anatomical and behavioral approaches to understand how receptors and signal transduction cascades contribute to chemosensory detection in olfactory, taste, and endocrine systems.
Department:
Orthodontics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
7/24/2017 9:53:20 AM
Research Description
Neurophysiology of pain; inflammation and neuropathic pain; chronic pain mechanisms; translational research for chronic pain.
Department:
Neuroscience
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/30/2020
Research Description
Our research focuses on understanding the underlying molecular mechanisms controlling gene expression in the inflammatory response and in the etiology of Type 1 Diabetes.
Department:
Psychiatry
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/30/2020
Research Description
Neurobehavioral and psychosocial concomitants of acute and chronic substance use, effects of aging, sex/gender differences, neurodevelopmental trajectories
Department:
Neurology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/16/2020
Research Description
Dr. Okun’s laboratory has focused on identifying the physiological brain signature patterns for tics and other movement disorders, and also has been focused on the development of neurotechnology for a closed loop solution to tic disorders. Dr. Okun’s research efforts have also been focused on the motor and non-motor aspects of deep brain stimulation as applied to basal ganglia disorders.
Department:
Biomedical Engineering
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/26/2017 12:45:56 PM
Research Description
Studies how stem cell strategies could be used to repair the brain. We use the hippocampus as a model to understand how make the brain receptive to neuron addition because the hippocampus adds new neurons throughout life in all mammals, including humans
Department:
Biomedical Engineering
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/15/2020
Research Description
Neural engineering. Sensory repair and prostheses. Brain-machine interfaces. Sensation induced by activation of neural tissue. Neural coding and plasticity.
Department:
Electrical and Computer Engineering
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/15/2020
Research Description
Sensorimotor Integration, Cognitive Skill Learning, Clinically Viable Brain Machine Interfaces, All optical electrophysiology, Movement disorders, spinal cord injury
Department:
Pharmacology & Therapeutics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/16/2020
Research Description
Physiology, pharmacology, and biophysics of neurotransmitter receptors especially the function of nicotinic acetylcholine receptors in the brain. We are additionally interested in addiction and the development of drug cessation therapies for smokers and people addicted to the use of betel quid.

Stefan Prokop, MD

Department:
Pathology, Immunology & Laboratory Medicine
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/15/2020
Research Description
As an experimental neuropathologist, Dr. Prokop combines both worlds of clinical service and basic research and, as a member of graduate student supervisory committees, he will use this expertise to emphasize similarities and differences between in vitro and animal model systems and the human disease situation. Dr. Prokop has been designated as the first Fixel Scholar and brings novel skills and scientific acumen to the field of neuromedicine.
Department:
Neurosurgery
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/15/2020
Research Description
Dr. Maryam Rahman is an assistant professor in the department of neurosurgery at the University of Florida. She specializes in the surgical treatment of brain tumors. Her research focuses on identifying novel immunotherapy approaches to overcome resistance in patients with brain cancer. Dr. Rahman’s work is supported by grants from the NIH, the Preston A. Wells Jr. endowment and private foundations. Her translational research in dendritic cell vaccines and immune checkpoint inhibitors is actively being tested in human clinical trials. She also dedicates her time to training the next generation and has been awarded multiple teaching awards including Outstanding Basic Science Teacher in 2016 and Exemplary Teacher award in 2018 and 2019. She currently serves as member at large of the CNS Executive Committee and serves as chair of online education, editor of Nexus, tumor section editor of SANS, editor of webinars and is faculty in the Leadership Institute.
Department:
Physiology & Functional Genomics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/22/2015
Research Description
Signal transduction mechanism of angiotensin regulation of norepinephrine neuromodulation in the brain; antisense targating of renin/angiotensin to control cardiovascular diseases; gene therapy, neurobiology, brain cytokines in neurogenic hypertension.
Department:
Molecular Genetics & Microbiology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/15/2020
Research Description
Uses human and mouse genetics to understand the causes and to develop therapies for genetic neurodegenerative diseases. A major focus in the lab is on diseases caused by repeat expansion mutations including amyotrophic lateral sclerosis (ALS), myotonic muscular dystrophy (DM1 and DM2) and spinocerebellar ataxias (SCA8).
Department:
Neurosurgery
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/15/2017 3:42:28 PM
Research Description
Characterization and manipulation of adult neural stem cells.
Department:
Neurology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/30/2020
Research Description
My laboratory applies a variety of techniques to study the molecular pathways associated with several neurodegenerative diseases and to discover potential therapeutic targets. To do so, we use a multidisciplinary approach combining Drosophila genetics, neuroscience, molecular and cellular biology, biochemistry and optogenetic technologies.
Department:
Neuroscience
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/15/2020
Research Description
Our research examines how cilia signaling contributes to brain development and cancer.
Department:
Neurosurgery
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/30/2020
Research Description
Current interests include developing innovative immunotherapeutics for pediatric tumors and invasive central nervous system malignancies. Dr. Sayour’s main focus is deeply rooted in harnessing the immune system to eradicate pediatric cancers. Dr. Sayour has extensive translational experience as PI/Co-I on several human trials (i.e. lead-PI on the first-in-human ACTION Trial- Adoptive Cellular Therapy following Dose-Intensified Temozolomide in Newly-diagnosed Pediatric High-grade Gliomas, NCT03334305). His translational efforts are also focused on new pipeline technologies including a novel lipid-nanoparticle (NP) formulation that he pioneered for the immunologic treatment of cancer. Dr. Sayour has spearheaded new paradigm treatments currently being tested in canine (pet dog) patients with terminal brain cancer (UFIACUC#201609430) before translation into dedicated human studies.
Department:
Physiology & Functional Genomics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/1/2016 12:31:28 PM
Research Description
Effects of stress and chronic elevations in glucocorticoids on central nervous system control of cardiovascular function.
Department:
Neuroscience
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/15/2020
Research Description
Research expertise: Inherited Photoreceptor disease, viral vector-based gene therapy, and circadian biology. My current focus is development of online and hybrid graduate courses and examination of effective approaches to graduate education.
Department:
Psychiatry
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/16/2020
Research Description
Behavioral and neurobiological basis of decision-making in relation to addiction and other psychiatric conditions. We employ a range of techniques, including behavioral pharmacology, optogenetics, and in vivo electrophysiology.

Alexandru Sheremet, DSc

Department:
Civil and Coastal Engineering
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/15/2020
Research Description
Nonlinear waves, nonlinear dynamical systems, stochastic processes, wave turbulence, soliton equations.
Department:
Ophthalmology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/16/2020
Research Description
Gene therapy of inherited retinal diseases
Department:
Neuroscience
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/15/2020
Research Description
Neuroimmunology and experimental neuropathology. Neurobiology of microglial cells.
Department:
Molecular Genetics & Microbiology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/16/2020
Research Description
Mouse models for neurological disease;RNA processing, transport and turnover; molecular mechanisms of mammalian development and aging
Department:
Neuroscience
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/16/2020
Research Description
The general interests of my laboratory include investigating the role and regulation of neuroinflammatory and immune system responses in modulating the gene-environment interactions that determine risk for development and progression of neurodegenerative and neuropsychiatric disease. We employ molecular, cellular, biochemical, pharmacological, immunohistological, fixed and live-cell high-content imaging, and behavioral assays to address important mechanistic questions with the long-term goal of developing novel therapeutics for the prevention and/or treatment of chronic neurodegenerative and neuropsychiatric diseases characterized by chronic neuroinflammation.
Department:
Neurosurgery
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/16/2020
Research Description
Research in the Tran lab focuses on understanding the molecular mechanism of how cancer develops, progresses, and resists treatments through an integrated approach from clinical observations to systems and computational biology, and to animal models and quantitative molecular validation, with the ultimate goal of returning to human patients to develop novel, safe and effective anti-cancer therapeutics.
Department:
Anatomy & Cell Biology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/16/2020
Research Description
The Vitriol lab uses live cell and super resolution microscopy to study the actin cytoskeleton in cell motility, neural development, and neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS).

Aparna Ashutosh Wagle Shukla

Department:
Neurology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/16/2020
Research Description
Physiology of Movement disorders (dystonia, tremor, Parkinson's disease)
Department:
Psychiatry
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/11/2018
Research Description
Protease and kinase in neruotrauma, neurodegeneration; Tauopathy/proteinopathy, biomarkers, proteomics, traumatic brain injury, spinal cord injury, substance abuse, exosome and microRNA pathways
Department:
Pharmacodynamics
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
No
Last Updated
6/15/2020
Research Description
Drug addiction appears to involve abnormally strong learned associations, typified by intrusive memories that often induce drug craving and relapse. Our research endeavors to decode how these drug memories are stored in the brain. We hypothesize that learned associations are encoded by patterns of sparsely distributed neurons, called neuronal ensembles, which are selected by cues and their reinforcers. Since strong neuronal activity drives expression of the immediate early gene Fos, we use Fos expression to identify neuronal ensembles activated during behavior. The relationship between neuronal activity and Fos expression permits us to use the Fos promoter to drive expression of transgenes in rats. Transgenic rat lines now allow us to characterize and manipulate neuronal ensembles with unmatched specificity. Understanding how these memories are encoded may one day enable us to treat drug addiction by strengthening or weakening specific drug or memories.
Department:
Psychiatry
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/11/2018
Research Description
Dr. Williamson has completed a clinical fellowship in neuropsychology and research fellowship in autonomic neuroscience. His research includes central and peripheral nervous system interactions in regulating behavior including cognition and emotion. He has active projects in mechanisms to PTSD associated with traumatic brain injury, cardiovascular disease contributions to cognitive impairment, sleep neuroscience, and the application of noninvasive nerve stimulation technologies to modify cognitive and emotional performance.
Department:
Physiology & Functional Genomics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/15/2020
Research Description
Fetal neuroendocrine development and cardiovascular physiology.
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/16/2020
Research Description
Cognitive function declines as we age. As our thinking and memory skills decline, the rate of functional dependence, mortality, and acute illness requiring hospitalization increases. A variety of methods have been proposed to counteract cognitive aging (e.g., cognitive training). Unfortunately, these techniques have limited degrees of success and transfer to everyday life. My work demonstrates that combining treatments like cognitive training with non-invasive brain stimulation (tDCS, TMS, tACS) facilitates neuroplastic response of brain tissue, improves cognitive abilities (specifically working memory, attention, and speed of processing), and leads to long-term improvement. In combination with modern multimodal neuroimaging and electrophysiology recording, this work not only identifies mechanisms underlying improvement, but also provides information important for further optimizing treatment effectiveness. Dr. Woods is PI of the largest NIH/NIA-funded Phase III tDCS trial, the ACT study. The ACT study investigates benefits of tDCS paired with cognitive training for cognitive and brain function and slowing onset of dementia in older adults.
Department:
Neurology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/15/2020
Research Description
He specializes in the diagnosis and management of neuromuscular diseases including amyotrophic lateral sclerosis (ALS) or Lou Gehrig’s disease, muscles diseases and peripheral neuropathies. Dr. Wymer has an extensive experience in clinical research, and has been the principal investigator in numerous clinical trials including studies of ALS, diabetic neuropathy, multiple sclerosis, migraine headaches and epilepsy. He is a fellow of the American Academy of Neurology (AAN) and the American Association of Neuromuscular and Electrodiagnostic Medicine (AANEM). He is a member of several national consortiums to research neuropathic pain and ALS.
Department:
Medicine-Jax
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/22/2015
Research Description
Role of H+ V-ATPase and novel secondary transporter Na+ or K+/H+ antiporter
Department:
Pediatrics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/30/2020
Research Description
Clinical genetics and cytogenetics, neurodevelopmental diseases.

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